Fri Aug 23 2024

18 articles - From Friday Aug 16 2024 to Friday Aug 23 2024

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr

Effects of prenatal small-quantity lipid-based nutrient supplements on pregnancy, birth and infant outcomes: a systematic review and meta-analysis of individual participant data from randomized controlled trials in low- and middle-income countries.

SQ-LNS had positive impacts on multiple outcomes compared to IFA/SOC, but further research directly comparing SQ-LNS and MMS is needed. Targeting SQ-LNS to vulnerable subgroups may be worth considering. Analysis registered at (CRD42021283391). REGISTRY AND REGISTRY NUMBER FOR SYSTEMATIC REVIEWS OR META-ANALYSES Registered at as CRD42021283391 on 11 April 2021.

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Pancreatology

Natural history of spontaneous pancreatic portal vein fistulae: A systematic review of the literature.

PPVF is a rare and potentially fatal condition, though rates of bleeding complication and death were relatively low in this population. High-quality observational studies are needed to better understand the pathophysiology and natural history of this diagnosis.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Association between dietary magnesium intake and incident chronic kidney disease : A prospective observational cohort study.

Lower dietary magnesium intake was associated with a higher risk of incident CKD in adults with clinically normal kidney function. Further controlled studies are required to establish the potential benefit of adequate magnesium intake.

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Association of ultra-processed food consumption with risk of rheumatoid arthritis: A retrospective cohort study in the UK Biobank.

Higher UPF consumption was associated with an increased risk of RA, which may be mediated by inflammation, lipids, and liver enzymes. Lower UPF consumption is recommended to reduce RA incidence.

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Calibration of 24-Hour Urinary Sodium Excretion Estimates from Fasting Morning Urine in Chinese Populations: A Comparative Analysis of Two Calibration Models and A Locally Developed Model.

The three evaluation models may serve as effective, low-burden alternatives for assessing urinary sodium levels in the population. However, to enhance the accuracy and reliability of predictions at the individual level, further repeated measurements are necessary to minimize measurement errors and augment the validity of the estimations.

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Diet Order Significantly Affects Energy Balance For Diets Varying In Macronutrients But Not Ultra-Processing In Crossover Studies Without A Washout Period.

Diet order significantly affected energy intake, body weight, and body fat in a 4-week crossover inpatient diet study varying in macronutrients, but not in a similarly structured study varying in ultra-processed foods. Clinical trial registration

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Inflamm Bowel Dis

The Composition of the Fecal and Mucosa-adherent Microbiota Varies Based on Age and Disease Activity in Ulcerative Colitis.

Our results indicate that pediatric UC patients have a more unstable fecal microbiota and a lower α diversity than adult patients and that the microbiota composition differs between aUC and pUC patients. These findings offer some explanation for the observed differences between pUC and aUC and indicate that individualized approaches are needed if microbiota modifications are to be used in the future treatment of UC.

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J Crohns Colitis

HLA-DQA1*05 associates with anti-TNF immunogenicity and low adalimumab trough concentrations in inflammatory bowel disease patients from the SERENE UC and CD studies.

We found a significant association between alleles at genes in the human HLA locus and the formation of adalimumab immunogenicity and low adalimumab drug-serum concentrations in large clinical studies of CD and UC patients. This work extends previous results in Crohn's disease to ulcerative colitis and directly shows a genetic association in patients with low drug concentrations. This work builds on existing literature to suggest genetic screening as a useful tool for clinicians concerned with patient anti-TNF immunogenicity.

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Pancreatology

Clinical impact of carbonic anhydrase 9 expression on neoadjuvant chemoradiotherapy in pancreatic ductal adenocarcinoma.

CA9 may act as a target molecule for RT/CRT, highlighting its clinical importance as a valuable biomarker for more stringent indications for NACRT.

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Relationships between postoperative recurrences and standardized uptake value on 18F-fluorodeoxyglucose-positron emission tomography in patients with resectable and borderline resectable pancreatic ductal adenocarcinoma who underwent curative pancreatic resection after neoadjuvant chemoradiotherapy.

R- and BR-PDACs with high SUV on FDG-PET at diagnosis are risk factors for postoperative recurrence. Among patients who undergo surgery after NACRT, those with a high SUVmax at diagnosis or post-NACRT require careful attention for postoperative liver recurrence.

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Severity and outcome of a first episode of idiopathic acute pancreatitis is not more severe than pancreatitis of other etiologies.

In the context of a first episode of acute pancreatitis, idiopathic acute pancreatitis remains a challenging diagnosis posing an increased risk of recurrence, but not an increased risk for a more severe disease course.

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The role of aspirin in the prevention of pancreatic cancer: A nested case-control study in the UK Biobank.

Regular aspirin use is associated with a reduction in risk of PDAC. The reduced risk is more apparent in participants with DM.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Inflamm Bowel Dis

In Severe Inflammatory Bowel Disease, the Onset of Effectiveness of Biologics and Small Molecules Depends More on the Medication Than on the Diagnosis.

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Liver Transpl

Unseen foe: The financial toxicity of liver transplantation.

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Pancreatology

Early discharge of patients with mild acute pancreatitis - A scoping review.

Early discharge of patients with mild acute pancreatitis seems both feasible and safe. Further studies are warranted, since focus on safe early discharge could significantly reduce inpatient healthcare utilization and associated costs.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…


Letters&Replies

Letters to the editors and authors’ replies

Inflamm Bowel Dis

Reply: In Severe Inflammatory Bowel Disease, the Onset of Effectiveness of Biologics and Small Molecules Depends More on the Medication Than on the Diagnosis.

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Pancreatology

Improving diagnostic accuracy of hidden pancreatic tumors on endoscopic ultrasound: Insights and methodological concerns on pancreatic juice cytology.

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Response to international evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas regarding EUS guided cyst chemoablation.

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